A 45-year-old woman presents with weight gain, moon face, and purple striae on her abdomen. What is the most likely diagnosis?

[dishita.s (Dishita Singh)]

These features are classic for Cushing’s syndrome, a condition caused by prolonged exposure to high levels of cortisol.
Common causes include:
• Exogenous corticosteroid use (most common overall)
• ACTH-secreting pituitary adenoma (Cushing’s disease)
• Adrenal adenoma or carcinoma
• Ectopic ACTH production (e.g., small cell lung cancer)